MiDOG Microbiome Dog Health Dermatitis Testing Infection Diagnosis

The MiDOG Test can help finding the cause of dermatitis

A recent study was conducted using MiDOG NGS technology to assess the skin fold microbiome in healthy French bulldogs. This study found that the primary skin bacterial phyla populating the nasomaxillary skin fold were Firmicutes, and Proteobacteria, while the primary skin fungal phyla were Ascomycota and Basidiomycota. Also, the researchers noted a significant correlation between the abundance of potentially opportunistic pathogens and microbial diversity. Healthy French bulldogs contained high ratios of clinically relevant pathogens (36.4%) in their nasomaxillary skin fold microbiome.

Additionally, the study looked at how topical treatment impacts the diversity of bacterial and fungal compositions over time, which is clinically useful because it can provide an alternative to antibiotic treatment. The dermal treatments analyzed in this study looked at a protease product (Kalzyme) that inhibits biofilm formation but has no biocidal activity and a 2% chlorhexidine diacetate (Nolvasan; CHX) solution, which has broad spectrum biocidal activity against bacteria and fungi. Interestingly, diversity increased by 38% for the protease group, as opposed to 11% for the CHX group.

Since the topical therapy with protease increases microbial diversity in the skin folds and reduces the relative abundance of pathogens, this therapy could hold clinical value in the treatment of intertrigo. As one of the researchers in this study, veterinary Dr. Alissa Rexo notes how “superficial bacterial pyoderma is one of the most common dermatologic diseases in dogs. Multi-drug antibiotic resistance has further complicated this problem and made both topical therapy selection and diagnostic testing of the utmost importance.” Considering intertrigo is one of the most common forms of surface pyoderma, it is important to ask your veterinarian for more information on treatment options.

If you would like to read the full study, please follow this link: https://onlinelibrary.wiley.com/doi/abs/10.1111/vde.13017

Alternatively, listen to a presentation by Dr. Rexo on this study in the link below:

MiDOG Swab Collection Kit

Find out if your vet uses MiDOG before you book your next appointment!

For health-related questions about the dermatologic status of your pet, reach out to a veterinarian that specializes in dermatology.


Categories: Skin Health

Validated by Veterinarians

“Clients expect their veterinarians to stay up to date on all matters that affect the health and well being of their non-human family members. The current technique that we have used to determine the presence and antibiotic sensitivity of organisms causing disease in our pets is over a century old.

With the emergence of dangerous antibacterial resistance, it is critical that veterinarians are able to offer laser focused diagnostics and treatment. MiDog enables us to offer care that exceeds the typical standard of care.”

Bernadine Cruz, DVM, Laguna Hills Animal Hospital Laguna Woods, CA

“I love the absolute abundance and comparing the fungal with bacterial infection. I do not worry as much about getting a false negative urinary infection reading as I do with traditional urine cultures. Several times the same urine would culture negative but MiDOG would detect pathogens.”

Michael Morgan, DVMQuail Animal Hospital, Tustin, CA

“The MiDOG All-in-One Test is amazing, I would use it instead of culture and sensitivity.  Such rapid and detailed results, I will reach for MiDOG before culture next time!

Thank you very much MiDOG, for sharing the opportunity to try your technology.”

Martha Smith-Blackmore, DVM, President of Forensic Veterinary Investigations, LLC – Boston, MA

The MiDOG All-in-One Microbial Test is our new gold standard of pathogen identification. The results are so accurate and valuable – especially with assessing both bacterial and fungal infections with the same sample.

Thank you MiDOG!”

Kathy Wentworth, DVM, Diplomate ABVP Canine and Feline Practice – PetPoint Medical Center, Irvine, CA

“The MiDOG staff was extremely helpful and supportive.”

Cathy Curtis, DVM – London, UK

“I have had great results using the MiDOG® Test. Compared to traditional culture tests, I am better able to target the treatment for dogs because the MiDOG® Test is so sensitive that it identifies all pathogens including bacteria and fungi, as well as antibiotic sensitivity.

The cost and turnaround time are about the same as a culture test, but I get much more data. The test has great performance and I believe the NGS technology will be a game changer for veterinarians treating dogs with lesions or other infections.”

Michael Kavanagh, DVM, Practice owner – Saddleback Animal Hospital, Tustin, CA